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Post-operative fracture risk assessment following tumor curettage in the distal femur: a hybrid in vitro and in silico biomechanical approach

Medicine and Health

Post-operative fracture risk assessment following tumor curettage in the distal femur: a hybrid in vitro and in silico biomechanical approach

A. Ghouchani, G. Rouhi, et al.

This groundbreaking study by Azadeh Ghouchani, Gholamreza Rouhi, and Mohammad Hosein Ebrahimzadeh introduces a biomechanical tool to evaluate post-operative fracture risk after distal femur tumor curettage. With the help of finite element models and quantitative CT imaging, the research uncovers critical insights into bone strength and reconstruction vulnerabilities.

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Playback language: English
Abstract
This study developed a biomechanical tool to assess post-operative fracture risk after distal femur tumor curettage. Using quantitative CT images, finite element (FE) models of cadaveric distal femora with simulated tumor defects were created and validated with in vitro tests. Analysis revealed that bone strength reduction was minimal until the defect reached 35% of epiphyseal volume, and lateral defects were stronger than medial ones. The proximal cortical window and the interior bone-cement interface were identified as vulnerable sites for reconstruction failure.
Publisher
Scientific Reports
Published On
Dec 07, 2020
Authors
Azadeh Ghouchani, Gholamreza Rouhi, Mohammad Hosein Ebrahimzadeh
Tags
biomechanical tool
post-operative fracture risk
distal femur
tumor curettage
bone strength
finite element models
reconstruction failure

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