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Review on the Safety and Efficacy of COVID-19 Vaccines Approved in Saudi Arabia

Medicine and Health

Review on the Safety and Efficacy of COVID-19 Vaccines Approved in Saudi Arabia

T. A. Alhandod, S. I. Rabbani, et al.

This systematic review delves into the safety and efficacy of four COVID-19 vaccines approved in Saudi Arabia, revealing crucial insights on local and systemic reactions, as well as highlighting the need for caution in specific populations. Conducted by Thekra Ali Alhandod, Syed Imam Rabbani, Mansour Almuqbil, Syed Arif Hussain, Nasser Fawzan Alomar, Manzoor Ahmad Mir, and Syed Mohammed Basheeruddin Asdaq, this research is a significant contribution to vaccine safety knowledge.

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Playback language: English
Abstract
This systematic review assesses the safety and efficacy of four COVID-19 vaccines (AstraZeneca, Pfizer, Moderna, and Janssen) approved in Saudi Arabia. Eighteen articles were analyzed, evaluating safety and efficacy across various demographics (male, female, over 18, those with comorbidities). Common local reactions included injection site pain, redness, swelling, and tenderness. Systemic reactions comprised fever, chills, fatigue, headache, and muscle pain. Efficacy exceeded the WHO threshold of 60%. However, the review highlights the need for caution in specific populations (pregnant, lactating, severely ill) and further research into rare, serious adverse events.
Publisher
Vaccines
Published On
Jan 28, 2023
Authors
Thekra Ali Alhandod, Syed Imam Rabbani, Mansour Almuqbil, Syed Arif Hussain, Nasser Fawzan Alomar, Manzoor Ahmad Mir, Syed Mohammed Basheeruddin Asdaq
Tags
COVID-19 vaccines
safety
efficacy
systemic reactions
adverse events
Saudi Arabia
comorbidities

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