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Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance

Medicine and Health

Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance

V. I. Gallardo-montejano, C. Yang, et al.

This groundbreaking study reveals how Perilipin 5 (PLIN5) levels surge in brown adipose tissue (BAT) during cold exposure, leading to enhanced fatty acid uptake and mitochondrial function. Conducted by renowned researchers including Violeta I. Gallardo-Montejano and Chaofeng Yang, the findings suggest that targeting PLIN5 could offer new therapeutic avenues for combating metabolic diseases.

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~3 min • Beginner • English
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