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Gastric emptying of a glucose drink is predictive of the glycaemic response to oral glucose and mixed meals, but unrelated to antecedent glycaemic control, in type 2 diabetes

Medicine and Health

Gastric emptying of a glucose drink is predictive of the glycaemic response to oral glucose and mixed meals, but unrelated to antecedent glycaemic control, in type 2 diabetes

C. Xiang, Y. Sun, et al.

This intriguing study explores how gastric emptying of a glucose drink can predict glycemic responses in individuals with type 2 diabetes, revealing an unexpected inverse relationship. Conducted by a team of experts including Chunjie Xiang and Yixuan Sun, the findings offer new insights into dietary management for diabetes patients.

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Playback language: English
Abstract
This study investigated the relationship between gastric emptying (GE) of a glucose drink and glycemic response in type 2 diabetes (T2D). Fifty-five treatment-naive Chinese adults with newly diagnosed T2D underwent continuous glucose monitoring and a 75g glucose drink test. Results showed an inverse relationship between glucose drink GE half-emptying time (T50) and glycemic response to both the glucose drink and mixed meals (breakfast and dinner). However, GE was unrelated to antecedent glycemic control. The study concludes that GE, measured using a standard glucose drink, predicts glycemic response to various meals in T2D, independent of prior glycemic levels.
Publisher
Nutrition and Diabetes
Published On
Apr 08, 2024
Authors
Chunjie Xiang, Yixuan Sun, Yong Luo, Cong Xie, Weikun Huang, Zilin Sun, Karen L. Jones, Michael Horowitz, Christopher K. Rayner, Jianhua Ma, Tongzhi Wu
Tags
gastric emptying
glycemic response
type 2 diabetes
glucose drink
continuous glucose monitoring
meal intake
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