This study investigated the effects of omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplementation on PM2.5-induced lung injury in mice. ω-3 PUFAs reduced lung injury, inflammation, and oxidative stress, altered lung metabolite profiles, and modulated the gut microbiota. Supplementation showed promise in attenuating PM2.5-induced lung injury.
Publisher
Environmental Science and Pollution Research
Published On
Jan 01, 2023
Authors
Jingli Li, Yang Chen, Qiangqiang Shi, Jian Sun, Chunyi Zhang, Lingjing Liu
Tags
omega-3 fatty acids
lung injury
PM2.5
inflammation
oxidative stress
gut microbiota
mice
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