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Neutralizing IFNγ Improves Safety without Compromising Efficacy of CAR-T Cell Therapy in B-cell Malignancies

Medicine and Health

Neutralizing IFNγ Improves Safety without Compromising Efficacy of CAR-T Cell Therapy in B-cell Malignancies

S. Manni, F. D. Bufalo, et al.

Discover groundbreaking research by Simona Manni and colleagues that reveals how IFNγ neutralization with emapalumab can reduce the severe side effects of CAR-T cell therapy, while preserving its effectiveness against B-cell malignancies. This study highlights a promising combination therapy approach that could transform treatment protocols.

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