Food Science and Technology

Muscle-derived fibro-adipogenic progenitor cells for production of cultured bovine adipose tissue

R. G. J. Dohmen, S. Hubalek, et al.

Discover how fibro-adipogenic progenitor cells (FAPs) can revolutionize cultured meat by mimicking traditional beef fat in flavor and texture. This groundbreaking research, conducted by a team of experts including Richard G. J. Dohmen and Sophie Hubalek, unveils the potential of FAPs for enhancing cultured fat production.

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Abstract

Cultured meat production requires fat tissue for flavor and texture. This study shows that fibro-adipogenic progenitor cells (FAPs) in bovine muscle, distinct from satellite cells, can be purified and efficiently expanded. FAPs exhibit high adipogenic potential, forming mature adipocytes in 3D hydrogels. The resulting cultured fat mimics traditional beef fat in lipid profile and taste, making FAPs a promising cell type for cultured fat production.

Publisher

npj Science of Food

Published On

Jan 24, 2022

Authors

Richard G. J. Dohmen, Sophie Hubalek, Johanna Melke, Tobias Messmer, Federica Cantoni, Arianna Mei, Rui Hueber, Rada Mitic, Dirk Remmers, Panagiota Moutsatsou, Mark J. Post, Laura Jackisch, Joshua E. Flack

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