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Abstract
This study investigated the effects of a fiber-rich fraction of partially defatted basil seeds (BSF) on insulin resistance (IR), hepatic steatosis, and fatty acid profiles in high-fat diet (HFD)-fed mice. Mice fed a HFD supplemented with BSF showed attenuated IR, steatosis, liver damage, oxidative stress, and inflammation, along with increased n-3 polyunsaturated fatty acids and short-chain fatty acid (SCFA) production, suggesting potential therapeutic benefits.
Publisher
npj Science of Food
Published On
Nov 08, 2024
Authors
Camila Farías, Camila Cisternas, Angie Caicedo, Lorena Mercado, Rodrigo Valenzuela, Héctor Calderón, Alejandra Espinosa, L. A. Videla, Loreto A. Muñoz
Tags
Insulin resistance
Hepatic steatosis
Basil seeds
High-fat diet
Therapeutic benefits
Polyunsaturated fatty acids
Short-chain fatty acids

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