Medicine and Health

High-fiber basil seed flour reduces insulin resistance and hepatic steatosis in high-fat diet mice

C. Farías, C. Cisternas, et al.

Discover how a fiber-rich fraction of partially defatted basil seeds can improve insulin resistance and liver health in high-fat diet-fed mice. This promising study conducted by Camila Farías, Camila Cisternas, Angie Caicedo, Lorena Mercado, Rodrigo Valenzuela, Héctor Calderón, Alejandra Espinosa, L. A. Videla, and Loreto A. Muñoz reveals significant therapeutic benefits worth exploring.

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Abstract

This study investigated the effects of a fiber-rich fraction of partially defatted basil seeds (BSF) on insulin resistance (IR), hepatic steatosis, and fatty acid profiles in high-fat diet (HFD)-fed mice. Mice fed a HFD supplemented with BSF showed attenuated IR, steatosis, liver damage, oxidative stress, and inflammation, along with increased n-3 polyunsaturated fatty acids and short-chain fatty acid (SCFA) production, suggesting potential therapeutic benefits.

Publisher

npj Science of Food

Published On

Nov 08, 2024

Authors

Camila Farías, Camila Cisternas, Angie Caicedo, Lorena Mercado, Rodrigo Valenzuela, Héctor Calderón, Alejandra Espinosa, L. A. Videla, Loreto A. Muñoz

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