Medicine and Health

Evaluation of care with intravitreal aflibercept treatment for UK patients with diabetic macular oedema: DRAKO study 24-month real-world outcomes

S. Sivaprasad, F. Ghanchi, et al.

The DRAKO study highlights the effectiveness of standard-of-care intravitreal aflibercept treatment for diabetic macular edema in the UK, showcasing impressive outcomes even with low injection frequencies. Conducted by an expert team of authors, the research reflects real-world clinical practices and maintains high patient quality-of-life scores.

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Abstract

The DRAKO study, a 24-month prospective observational multi-center cohort study, evaluated standard-of-care intravitreal aflibercept (IVT-AFL) treatment for diabetic macular edema (DMO) in the UK. The study analyzed 12-month outcomes for patients with prior anti-VEGF treatment (C2) and 2-year outcomes for anti-VEGF-naïve (C1) and C2 patients. Results showed IVT-AFL was effective, with improvements in BCVA and CST, even with relatively low injection numbers. High baseline visual and quality-of-life scores were maintained, indicating the effectiveness of IVT-AFL in real-world UK clinical practice.

Publisher

Eye

Published On

Mar 20, 2023

Authors

Sobha Sivaprasad, Faruque Ghanchi, Simon P. Kelly, Ajay Kotagiri, James Talks, Peter Scanlon, Hellen McGoey, Andrew Nolan, Moneeb Saddiq, Jackie Napier

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