This retrospective cohort study investigated the prognostic value of lymph node ratio (LNR) compared to pN stage in non-small cell lung cancer (NSCLC) patients undergoing surgery. Using data from the Surveillance, Epidemiology, and End Results (SEER) databases (2004-2015), the study found that LNR, categorized into three groups (LNR1, LNR2, LNR3), significantly predicted cancer-specific survival (CSS) and overall survival (OS). A revised pN (r-pN) classification incorporating LNR and pN showed superior predictive performance than either LNR or pN alone. The findings suggest LNR is a valuable prognostic factor for NSCLC patients and could improve adjuvant treatment decisions.
Publisher
Journal of Cancer
Published On
Jan 01, 2024
Authors
Shou-Feng Wang, Nai-Quan Mao, Jiang-Qiong Huang, Xin-Bin Pan
Tags
lymph node ratio
non-small cell lung cancer
prognostic factor
cancer-specific survival
overall survival
pN stage
adjuvant treatment
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