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Development of a 1,3a,6a-triazapentalene derivative as a compact and thiol-specific fluorescent labeling reagent

Chemistry

Development of a 1,3a,6a-triazapentalene derivative as a compact and thiol-specific fluorescent labeling reagent

A. Nakayama, A. Otani, et al.

Discover the groundbreaking fluorescent labeling reagent, TAP-VK1, developed by Atsushi Nakayama and colleagues, which specifically reacts with aliphatic thiols, significantly boosting fluorescence intensity. This innovative approach has enabled effective fluorescence imaging of Captopril in living cells, showcasing a leap in chemical sensing technology.

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