This study investigated the combined associations of 25-hydroxyvitamin D [25(OH)D] and parathyroid hormone (PTH) with diabetes risk and related comorbidities in white and black postmenopausal women. Lower 25(OH)D and higher PTH were linked to higher hypertension prevalence in white women. Vitamin D deficiency and PTH excess were associated with increased prevalence of CKD, hypertension, or obesity in non-diabetic women. Prospectively, lower 25(OH)D was associated with lower diabetes incidence in white women, with vitamin D deficiency increasing diabetes risk regardless of PTH levels.
Publisher
Nutrition and Diabetes
Published On
Sep 16, 2021
Authors
Jin Xia, Wanzhu Tu, JoAnn E. Manson, Hongmei Nan, Aladdin H. Shadyab, Jennifer W. Bea, Emily W. Gower, Lihong Qi, Ting-Yuan David Cheng, Yiqing Song
Tags
25-hydroxyvitamin D
parathyroid hormone
diabetes risk
comorbidities
postmenopausal women
hypertension
vitamin D deficiency
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