logo
ResearchBunny Logo
Targeting IL-21 to tumor-reactive T cells enhances memory T cell responses and anti-PD-1 antibody therapy

Medicine and Health

Targeting IL-21 to tumor-reactive T cells enhances memory T cell responses and anti-PD-1 antibody therapy

Y. Li, Y. Cong, et al.

Exciting advancements in cancer therapy are on the horizon! This study by Ying Li and colleagues reveals that an innovative IL-21-anti-PD-1 antibody fusion protein significantly enhances memory T cell generation and boosts antitumor effects in mice, surpassing traditional PD-1 blockade methods. Discover how this could reshape immune checkpoint therapies!

00:00
00:00
Playback language: English
Citation Metrics
Citations
0
Influential Citations
0
Reference Count
0

Note: The citation metrics presented here have been sourced from Semantic Scholar and OpenAlex.

Related Publications

Explore these studies to deepen your understanding of the subject.

Adapter CAR T cells to counteract T-cell exhaustion and enable flexible targeting in AML
Medicine and Health

Adapter CAR T cells to counteract T-cell exhaustion and enable flexible targeting in AML

D. Nixdorf, M. Sponheimer, et al.

IL-15 armoring enhances the antitumor efficacy of claudin 18.2-targeting CAR-T cells in syngeneic mouse tumor models
Medicine and Health

IL-15 armoring enhances the antitumor efficacy of claudin 18.2-targeting CAR-T cells in syngeneic mouse tumor models

H. Shi, A. Li, et al.

Locoregional delivery of IL-13Rx2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial
Medicine and Health

Locoregional delivery of IL-13Rx2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial

C. E. Brown, J. C. Hibbard, et al.

TLR5 agonists enhance anti-tumor immunity and overcome resistance to immune checkpoint therapy
Medicine and Health

TLR5 agonists enhance anti-tumor immunity and overcome resistance to immune checkpoint therapy

C. Gonzalez, S. Williamson, et al.

Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny