Biology

Supporting Information Nano-brake Halts Mitochondrial Dysfunction Cascade to Alleviate Neuropathology and Rescue Alzheimer's Cognitive Deficits

Q. Zhang, Q. Song, et al.

This groundbreaking research by Qian Zhang and colleagues reveals how the innovative nanocarrier 'Nano-brake' effectively addresses mitochondrial dysfunction in Alzheimer's disease by delivering cyclophilin D siRNA across the blood-brain barrier. The findings highlight its potential to enhance cognitive function and reduce neuroinflammation in transgenic AD mice.... show more

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