logo
ResearchBunny Logo
Supporting Information Nano-brake Halts Mitochondrial Dysfunction Cascade to Alleviate Neuropathology and Rescue Alzheimer's Cognitive Deficits

Biology

Supporting Information Nano-brake Halts Mitochondrial Dysfunction Cascade to Alleviate Neuropathology and Rescue Alzheimer's Cognitive Deficits

Q. Zhang, Q. Song, et al.

This groundbreaking research by Qian Zhang and colleagues reveals how the innovative nanocarrier 'Nano-brake' effectively addresses mitochondrial dysfunction in Alzheimer's disease by delivering cyclophilin D siRNA across the blood-brain barrier. The findings highlight its potential to enhance cognitive function and reduce neuroinflammation in transgenic AD mice.

00:00
00:00
~3 min • Beginner • English
Abstract
Publisher
Nature Communications (example)
Published On
Jan 01, 2023
Authors
Qian Zhang, Qingxiang Song, Renhe Yu, Antian Wang, Gan Jiang, Yukun Huang, Jun Chen, Jianrong Xu, Dayuan Wang, Hongzhuan Chen, Xiaoling Gao
Tags
Alzheimer's disease
Nano-brake
mitochondrial dysfunction
CypD siRNA
blood-brain barrier
neuroinflammation
cognitive function

Related Publications

Explore these studies to deepen your understanding of the subject.

Targeting neurotrophin and nitric oxide signaling to promote recovery and ameliorate neurogenic bladder dysfunction following spinal cord injury -Mechanistic concepts and clinical implications
Biology

Targeting neurotrophin and nitric oxide signaling to promote recovery and ameliorate neurogenic bladder dysfunction following spinal cord injury -Mechanistic concepts and clinical implications

A. J. Kanai, K. Andersson, et al.

Reliability and accuracy of artificial intelligence ChatGPT in providing information on ophthalmic diseases and management to patients
Medicine and Health

Reliability and accuracy of artificial intelligence ChatGPT in providing information on ophthalmic diseases and management to patients

F. Cappellani, K. R. Card, et al.

Assessing the factors influencing the intention to use information and communication technology implementation and acceptance in China's education sector
Education

Assessing the factors influencing the intention to use information and communication technology implementation and acceptance in China's education sector

M. F. Shahzad, S. Xu, et al.

Galactooligosaccharides and *Limosilactobacillus reuteri* synergistically alleviate gut inflammation and barrier dysfunction by enriching *Bacteroides acidifaciens* for pentadecanoic acid biosynthesis
Medicine and Health

Galactooligosaccharides and *Limosilactobacillus reuteri* synergistically alleviate gut inflammation and barrier dysfunction by enriching *Bacteroides acidifaciens* for pentadecanoic acid biosynthesis

Y. Wu, X. Zhang, et al.

Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny