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Spatial proteomics identifies JAKi as treatment for a lethal skin disease

Medicine and Health

Spatial proteomics identifies JAKi as treatment for a lethal skin disease

T. M. Nordmann, H. Anderton, et al.

A groundbreaking study by Thierry M. Nordmann and colleagues reveals that targeting JAK inhibitors could be a transformative therapy for toxic epidermal necrolysis (TEN), a severe drug-induced skin reaction. Through deep visual proteomics analysis, the research identified key activation signatures in TEN, demonstrating the promise of JAK inhibitors in improving patient outcomes.... show more
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