Medicine and Health

Mediterranean diet as a strategy for preserving kidney function in patients with coronary heart disease with type 2 diabetes and obesity: a secondary analysis of CORDIOPREV randomized controlled trial

A. Podadera-herreros, A. P. A. Larriva, et al.

This groundbreaking study by Alicia Podadera-Herreros and team unveils the alarming effects of obesity on kidney function in patients suffering from type 2 diabetes and coronary heart disease. With a focus on the Mediterranean diet, the research highlights its remarkable ability to slow down kidney decline in these vulnerable patients. Dive into the findings that could reshape dietary recommendations for better kidney health!

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Abstract

This study investigated the impact of obesity on kidney function in patients with type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD). 1002 patients were randomized to a Mediterranean diet or a low-fat diet for 5 years. Patients with Obesity/T2DM had the lowest baseline eGFR and highest uACR. The Mediterranean diet showed a lower eGFR decline and reduced uACR in Obesity/T2DM patients compared to the low-fat diet. Obesity exacerbated kidney dysfunction in T2DM patients. The Mediterranean diet was more beneficial for preserving kidney function in patients with T2DM and obesity.

Publisher

Nutrition and Diabetes

Published On

May 16, 2024

Authors

Alicia Podadera-Herreros, Antonio P. Arenas-de Larriva, Francisco M. Gutierrez-Mariscal, Juan F. Alcala-Diaz, Ana Ojeda-Rodriguez, Fernando Rodriguez-Cantalejo, Magdalena P. Cardelo, Diego Rodriguez-Cano, Jose D. Torres-Peña, Raul M. Luque, Jose M. Ordovas, Pablo Perez-Martinez, Javier Delgado-Lista, Jose Lopez-Miranda, Elena M. Yubero-Serrano

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