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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

Medicine and Health

Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

C. Lund, P. Ranea-robles, et al.

Discover groundbreaking insights from Camilla Lund and her colleagues at the Novo Nordisk Foundation Center for Basic Metabolic Research, as they unveil how both lean and diet-induced obese male mice can combat weight gain after overfeeding. Their research highlights the role of novel circulating factors and challenges the necessity of FGF21 in this complex mechanism.

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