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Prior SARS-CoV-2 Infection Enhances Initial mRNA Vaccine Response with a Lower Impact on Long-Term Immunity

Biology

Prior SARS-CoV-2 Infection Enhances Initial mRNA Vaccine Response with a Lower Impact on Long-Term Immunity

Silva-moraes, Souquette, et al.

This study reveals intriguing insights into the adaptive immune responses generated after three doses of the Pfizer BNT162b2 mRNA vaccine in both SARS-CoV-2-naive and preimmune individuals. Conducted by Silva-Moraes, Souquette, A Sautto, Ida Paciello, Giada Antonelli, Emanuele Andreano, Rappuoli, Andr M Ea Teixeira-Carvalho, and DrTed M Ross, it highlights how prior infections significantly influence antibody levels while emphasizing the overall immune memory after vaccination.

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