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Mucosa-Associated Microbiota and Metabolome in Colorectal Polyps: A Novel Sampling Strategy Reveals Tumor Stage-Specific Signatures

Medicine and Health

Mucosa-Associated Microbiota and Metabolome in Colorectal Polyps: A Novel Sampling Strategy Reveals Tumor Stage-Specific Signatures

M. Clavenna, M. L. Vecchia, et al.

This groundbreaking study by M.G. Clavenna and colleagues uncovers the intricate relationship between gut microbiota and metabolome composition in relation to colorectal cancer (CRC). With a novel sampling technique, they reveal striking microbial and metabolic differences between polyps of varying dysplasia grades, providing compelling insights into CRC initiation and progression.

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~3 min • Beginner • English
Abstract
Publisher
Cancers
Published On
Dec 15, 2023
Authors
M.G. Clavenna, M. La Vecchia, M. Sculco, S. Joseph, E. Barberis, E. Amede, M. Mellai, S. Brossa, G. Borgonovi, P. Occhipinti, R. Boldorini, E. Robotti, A. Aspesi, I. Degano, A. Aimaretti
Tags
gut microbiota
metabolome
colorectal cancer
dysplastic polyps
microbial signatures
metabolic signatures
bacteria

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