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Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy

Biology

Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy

J. Zhao, L. Jiang, et al.

Discover the groundbreaking Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT), developed by Jian Zhao and colleagues, which enables detailed chemical-specific imaging of tau fibrils in their native cellular environment, revealing intriguing links between lipid accumulation and tau aggregation.

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