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Mesenchymal stem cell-derived exosomes as a promising cell-free therapy for knee osteoarthritis

Medicine and Health

Mesenchymal stem cell-derived exosomes as a promising cell-free therapy for knee osteoarthritis

D. Luo, H. Zhu, et al.

Osteoarthritis (OA) is a debilitating disease with substantial socioeconomic implications. Current treatments primarily alleviate symptoms rather than addressing disease progression. This innovative study, conducted by Danni Luo and colleagues, delves into the potential of mesenchymal stem cell-derived exosomes in OA treatment, revealing mechanisms, strategies, and future challenges.

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Playback language: English
Abstract
Osteoarthritis (OA) is a degenerative joint disease causing significant socioeconomic burden. Current treatments focus on symptom relief, not disease progression. Mesenchymal stem cell-derived exosomes (MSC-Exos) show promise in OA treatment. This study reviews MSC-Exo applications in OA, exploring underlying mechanisms, current strategies, and future challenges.
Publisher
Frontiers in Bioengineering and Biotechnology
Published On
Jan 16, 2024
Authors
Danni Luo, Hao Zhu, Song Li, Zhenggang Wang, Jun Xiao, Chiara Gentili, Shi-Cong Tao, Fengyuan Zhao
Tags
Osteoarthritis
degenerative joint disease
mesenchymal stem cells
exosomes
disease progression
treatment strategies
recovery mechanisms

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