This 10-year follow-up study of a first-episode psychosis (FEP) cohort investigated clinical recovery (CR) and treatment resistance (TR). At 10 years, 29% were in CR, 31% were TR, and 40% were in partial recovery. Insidious onset and baseline disorganized symptoms predicted TR, while acute onset, good premorbid academic adjustment, and non-schizophrenia diagnosis predicted CR. The study highlights the importance of early-course parameters in predicting long-term outcomes and the need for adequate treatment.
Publisher
Schizophrenia
Published On
Aug 22, 2024
Authors
Kristin Fjelnseth Wold, Isabel Viola Kreis, Gina Åsbø, Camilla Bärthel Flaaten, Line Widing, Magnus Johan Engen, Siv Hege Lyngstad, Erik Johnsen, Torill Ueland, Carmen Simonsen, Ingrid Melle
Tags
first-episode psychosis
clinical recovery
treatment resistance
long-term outcomes
mental health
symptoms
intervention
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