Medicine and Health

A synergistic impact of body mass index and gamma gap on heart failure and mortality rate among older patients with coronary artery disease: a prospective study with 10-year follow-up

X. Liu, Y. Zheng, et al.

This groundbreaking 10-year study reveals alarming insights into how body mass index and gamma gap levels impact heart failure and mortality in older coronary artery disease patients. Conducted by Xiaofei Liu and colleagues, the findings highlight a significant risk associated with low BMI and high gamma gap—inviting further exploration into effective interventions.

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Abstract

This prospective 10-year study investigated the combined effects of body mass index (BMI) and gamma gap on heart failure and mortality in older coronary artery disease (CAD) patients. Patients were divided into four groups based on BMI and gamma gap levels. The highest heart failure (46.2%) and mortality (84.4%) rates were in the low BMI, high gamma gap group, while the lowest rates (18.9% and 62.9%, respectively) were in the high BMI, low gamma gap group. Multivariate analyses confirmed a synergistic effect of low BMI and high gamma gap on increased heart failure and mortality risk. Further research is needed to explore underlying mechanisms and potential interventions.

Publisher

Nutrition and Diabetes

Published On

Dec 05, 2023

Authors

Xiaofei Liu, Yangrui Zheng, Da Li, Yali Zhao, Houchen Lv, Lixun Guan, Shihui Fu

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