Psychology

Long-term clinical recovery and treatment resistance in first-episode psychosis: a 10-year follow-up study

K. F. Wold, I. V. Kreis, et al.

Discover the long-term outcomes of first-episode psychosis in this compelling 10-year follow-up study. Conducted by esteemed researchers including Kristin Fjelnseth Wold and Isabel Viola Kreis, the research reveals intriguing statistics about clinical recovery and treatment resistance, emphasizing the critical nature of early treatment interventions.

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Abstract

This 10-year follow-up study of a first-episode psychosis (FEP) cohort investigated clinical recovery (CR) and treatment resistance (TR). At 10 years, 29% were in CR, 31% were TR, and 40% were in partial recovery. Insidious onset and baseline disorganized symptoms predicted TR, while acute onset, good premorbid academic adjustment, and non-schizophrenia diagnosis predicted CR. The study highlights the importance of early-course parameters in predicting long-term outcomes and the need for adequate treatment.

Publisher

Schizophrenia

Published On

Aug 22, 2024

Authors

Kristin Fjelnseth Wold, Isabel Viola Kreis, Gina Åsbø, Camilla Bärthel Flaaten, Line Widing, Magnus Johan Engen, Siv Hege Lyngstad, Erik Johnsen, Torill Ueland, Carmen Simonsen, Ingrid Melle

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