This study introduces a fully bioresorbable flexible hybrid opto-electronic system for simultaneous electrophysiological recording and optogenetic stimulation. The device, composed of biodegradable materials, has a direct optical and electrical interface with the brain, exhibiting excellent biocompatibility. Chronically implanted in transgenic mice, it successfully photostimulated the somatosensory area while recording local field potentials. This system promises versatile applications in biomedicine.
Publisher
Nature Communications
Published On
Mar 06, 2024
Authors
Myeongki Cho, Jeong-Kyu Han, Jungmin Suh, Jeong Jin Kim, Jae Ryun Ryu, In Sik Min, Mingyu Sang, Selin Lim, Tae Soo Kim, Kyubeen Kim, Kyowon Kang, Kyuhyun Hwang, Kanghwan Kim, Eun-Bin Hong, Min-Ho Nam, Jongbaeg Kim, Young Min Song, Gil Ju Lee, Il-Joo Cho, Ki Jun Yu
Tags
bioresorbable
opto-electronic system
electrophysiological recording
optogenetic stimulation
biocompatibility
transgenic mice
biomedicine
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