Medicine and Health

Effects of the WHO Labour Care Guide on cesarean section in India: a pragmatic, stepped-wedge, cluster-randomized pilot trial

J. P. Vogel, Y. Pujar, et al.

Explore the findings of a pilot trial conducted across four Indian hospitals, examining the impact of the WHO Labour Care Guide strategy on cesarean section rates. The trial observed a 5.5% absolute reduction in cesarean rates with the strategy, highlighting key insights and a need for further research. Authors, including Joshua P. Vogel and Yeshita Pujar, contributed to this important study in maternal health.

00:00

Playback language: English

Index

Abstract

Cesarean section rates are rising globally due to medically unnecessary procedures. This stepped-wedge, cluster-randomized pilot trial in four Indian hospitals evaluated the World Health Organization Labour Care Guide (LCG) strategy intervention against routine care. The primary outcome (cesarean rate in Robson Group 1) showed a 5.5% crude absolute reduction (45.2% vs 39.7%), though not statistically significant. Labor augmentation with oxytocin was significantly lower with the LCG strategy. Other outcomes showed no significant differences. Findings suggest the LCG strategy warrants further investigation in larger trials.

Publisher

Nature Medicine

Published On

Feb 16, 2024

Authors

Joshua P. Vogel, Yeshita Pujar, Sunil S. Vernekar, Elizabeth Armari, Veronica Pingray, Fernando Althabe, Luz Gibbons, Mabel Berrueta, Manjunath Somannavar, Alvaro Ciganda, Rocio Rodriguez, Savitri Bendigeri, Jayashree Ashok Kumar, Shruti Bhavi Patil, Aravind Karinagannanavar, Raveendra R. Anteens, Pavithra Mallappa Ramachandrappas, Shukla Shetty, Latha Bommanal, Megha Haralahalli Mallesh, Suman S. Gaddi, Shaila Chikkagowdra, Bellara Raghavendra, Caroline S. E. Homer, Tina Lavender, Pralhad Kushtagi, G. Justus Hofmeyr, Richard Derman, Shivaprasad Goudar

Related Publications

Explore these studies to deepen your understanding of the subject.

Medicine and Health

A pilot randomized controlled trial investigating the effects of an anti-inflammatory dietary pattern on disease activity, symptoms and microbiota profile in adults with inflammatory bowel disease

A. Marsh, V. Chachay, et al.

Medicine and Health

Effects of Mediterranean diet during pregnancy on the onset of overweight or obesity in the offspring: a randomized trial

S. Coppola, L. Paparo, et al.

Medicine and Health

The effects of omega 3 fatty acids on the serum concentrations of pro inflammatory cytokines and depression status in patients with bipolar disorder: A randomized double-blind controlled clinical trial

H. Eslahi, M. Shakiba, et al.

Medicine and Health

Effects of yoga in men with prostate cancer on quality of life and immune response: a pilot randomized controlled trial

D. Kaushik, P. K. Shah, et al.

Listen, Learn & Level Up

Over 10,000 hours of research content in 25+ fields, available in 12+ languages.

No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.

listen to research audio papers with researchbunny