Medicine and Health

Effects of Nordic walking in Alzheimer's disease: A single-blind randomized controlled clinical trial

A. Angiolillo, D. Leccese, et al.

This clinical trial explored the intriguing effects of a 24-week Nordic walking program on cognitive decline in individuals with mild to moderate Alzheimer's disease. Although the primary outcomes didn’t show significant change, notable improvements in executive functions and memory were observed. Conducted by a dedicated team of researchers, these findings propose a promising intervention strategy worth further exploration.

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Abstract

This single-blind randomized controlled clinical trial investigated the effects of a 24-week Nordic walking (NW) training program on cognitive function in patients with mild/moderate Alzheimer's disease (AD). While the primary outcome (24-week change in MMSE scores) showed no significant difference between the NW group and the control group, secondary outcomes revealed significant improvements in the NW group for executive functions (FAB), selective attention and processing speed (SWCT), visual-spatial reasoning (CPM), and verbal episodic memory (RAVLT delayed recall). These findings suggest NW may offer a safe and effective strategy to decelerate cognitive decline in mild/moderate AD, warranting further research with larger samples and longer durations.

Publisher

Heliyon

Published On

Apr 28, 2023

Authors

A Angiolillo, D Leccese, S Ciccotelli, G Di Cesare, K D'elia, N Aurisano, C Matrone, C Dentizzi, A Di Costanzo

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