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Directed self-assembly of a xenogeneic vascularized endocrine pancreas for type 1 diabetes

Medicine and Health

Directed self-assembly of a xenogeneic vascularized endocrine pancreas for type 1 diabetes

A. Citro, A. Neroni, et al.

This groundbreaking research proposes using decellularized lungs as scaffolds for xenogeneic vascularized endocrine pancreas engineering, combining neonatal porcine islets with human endothelial cells. Conducted by a team from the San Raffaele Diabetes Research Institute in Milan, this study reveals promising results in islet maturation and sustained normoglycemia, paving the way for advanced diabetes treatments.

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