This study presents a novel ‘cavitation-on-a-chip’ device featuring eight parallel microchannels designed to reduce the upstream pressure needed for hydrodynamic cavitation. Using water and a poly(vinyl alcohol) (PVA) microbubble suspension, the device demonstrated a lower cavitation inception pressure compared to single-channel devices. The device also exhibited varied cavitation flow patterns at constant cavitation number and upstream pressure. Its potential applications include microfluidic/organ-on-a-chip devices for drug release and tissue engineering.
Publisher
Microsystems & Nanoengineering
Published On
Authors
Farzad Rokhsar Talabazar, Mohammad Jafarpour, Merve Zuvin, Hongjian Chen, Moein Talebian Gevari, Luis Guillermo Villanueva, Dmitry Grishenkov, Ali Koşar, Morteza Ghorbani
Tags
cavitation-on-a-chip
microchannels
hydrodynamic cavitation
drug release
tissue engineering
poly(vinyl alcohol)
microfluidics
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