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Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration

Engineering and Technology

Design and fabrication of a vigorous “cavitation-on-a-chip” device with a multiple microchannel configuration

F. R. Talabazar, M. Jafarpour, et al.

Discover the groundbreaking 'cavitation-on-a-chip' device developed by Farzad Rokhsar Talabazar and his team, featuring eight innovative microchannels that significantly lower the pressure needed for hydrodynamic cavitation. This advancement opens doors for applications in drug delivery and tissue engineering.

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Playback language: English
Abstract
This study presents a novel ‘cavitation-on-a-chip’ device featuring eight parallel microchannels designed to reduce the upstream pressure needed for hydrodynamic cavitation. Using water and a poly(vinyl alcohol) (PVA) microbubble suspension, the device demonstrated a lower cavitation inception pressure compared to single-channel devices. The device also exhibited varied cavitation flow patterns at constant cavitation number and upstream pressure. Its potential applications include microfluidic/organ-on-a-chip devices for drug release and tissue engineering.
Publisher
Microsystems & Nanoengineering
Published On
Authors
Farzad Rokhsar Talabazar, Mohammad Jafarpour, Merve Zuvin, Hongjian Chen, Moein Talebian Gevari, Luis Guillermo Villanueva, Dmitry Grishenkov, Ali Koşar, Morteza Ghorbani
Tags
cavitation-on-a-chip
microchannels
hydrodynamic cavitation
drug release
tissue engineering
poly(vinyl alcohol)
microfluidics
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