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Baseline ctDNA gene alterations as a biomarker of survival after panitumumab and chemotherapy in metastatic colorectal cancer

Medicine and Health

Baseline ctDNA gene alterations as a biomarker of survival after panitumumab and chemotherapy in metastatic colorectal cancer

K. Shitara, K. Muro, et al.

In the exciting Phase 3 PARADIGM trial involving 733 participants, researchers investigated how circulating tumor DNA (ctDNA) gene alterations impact treatment outcomes in RAS wild-type metastatic colorectal cancer. Discover whether first-line therapy using panitumumab could provide longer survival rates for patients without ctDNA alterations, as highlighted by the team of experts led by Kohei Shitara and Kei Muro.

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