Medicine and Health

Comparing the efficacy and pregnancy outcome of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation after hysteroscopic adhesiolysis in infertile women: a prospective, randomized, controlled trial study

Q. Zhang, H. Ding, et al.

This groundbreaking trial led by Qing Zhang and colleagues explores the effectiveness of intrauterine balloons versus IUDs in preventing adhesion reformation after hysteroscopic adhesiolysis. Discover how these interventions could enhance treatment outcomes for infertile women facing moderate to severe intrauterine adhesions.

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~3 min • Beginner • English

Index

Abstract

Study objective: To evaluate the efficacy and pregnancy outcomes of intrauterine balloon and intrauterine contraceptive device (IUD) in preventing adhesion reformation after hysteroscopic adhesiolysis (TCRA) in infertile women with moderate to severe intrauterine adhesions (IUA). Design: Prospective, randomized, controlled trial. Setting: Tertiary university hospital. Patients: 130 women with moderate (AFS 5–8) or severe (AFS 9–12) IUA. Interventions: IUD for 1 month, IUD for 2 months, or a Foley catheter balloon for 5 days. Measurements and main results: Primary outcomes were AFS score change, endometrial thickness, and pregnancy outcomes. Postoperatively, AFS scores decreased significantly in all groups and endometrial thickness increased. The reduction in AFS score was greater in the balloon group than in either IUD group, while increases in endometrial thickness and pregnancy outcomes did not differ significantly among groups.

Publisher

Reproductive Biology and Endocrinology

Published On

Apr 13, 2024

Authors

Qing Zhang, Haixia Ding, Honghong Zhang, Rui Qiao, Ningxia Sun, Yixuan Ji, Wenjuan Pang, Wen Li

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