This prospective, randomized, controlled trial evaluated the efficacy of intrauterine balloon and intrauterine contraceptive devices (IUDs) in preventing adhesion reformation after hysteroscopic adhesiolysis in 130 infertile women with moderate to severe intrauterine adhesions. The primary outcomes were AFS score, endometrial thickness, and pregnancy outcome. Both IUD placement (1 or 2 months) and balloon placement (5 days) significantly reduced the AFS score post-surgery compared to pre-surgery. The balloon group showed a greater reduction in AFS score than the IUD groups, although the difference in endometrial thickness and pregnancy rates among the three groups was not statistically significant. The study suggests that both methods are effective in preventing adhesion recurrence, with balloon placement potentially offering a superior effect on uterine morphology restoration.
Publisher
Reproductive Biology and Endocrinology
Published On
Apr 13, 2024
Authors
Qing Zhang, Haixia Ding, Honghong Zhang, Rui Qiao, Ningxia Sun, Yixuan Ji, Wenjuan Pang, Wen Li
Tags
intrauterine balloon
IUD
adhesion reformation
hysteroscopic adhesiolysis
infertility
clinical trial
AFS score
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