Medicine and Health

Comparing the efficacy and pregnancy outcome of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation after hysteroscopic adhesiolysis in infertile women: a prospective, randomized, controlled trial study

Q. Zhang, H. Ding, et al.

This groundbreaking trial led by Qing Zhang and colleagues explores the effectiveness of intrauterine balloons versus IUDs in preventing adhesion reformation after hysteroscopic adhesiolysis. Discover how these interventions could enhance treatment outcomes for infertile women facing moderate to severe intrauterine adhesions.

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Index

Abstract

This prospective, randomized, controlled trial evaluated the efficacy of intrauterine balloon and intrauterine contraceptive devices (IUDs) in preventing adhesion reformation after hysteroscopic adhesiolysis in 130 infertile women with moderate to severe intrauterine adhesions. The primary outcomes were AFS score, endometrial thickness, and pregnancy outcome. Both IUD placement (1 or 2 months) and balloon placement (5 days) significantly reduced the AFS score post-surgery compared to pre-surgery. The balloon group showed a greater reduction in AFS score than the IUD groups, although the difference in endometrial thickness and pregnancy rates among the three groups was not statistically significant. The study suggests that both methods are effective in preventing adhesion recurrence, with balloon placement potentially offering a superior effect on uterine morphology restoration.

Publisher

Reproductive Biology and Endocrinology

Published On

Apr 13, 2024

Authors

Qing Zhang, Haixia Ding, Honghong Zhang, Rui Qiao, Ningxia Sun, Yixuan Ji, Wenjuan Pang, Wen Li

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