Medicine and Health

An injectable photopolymerized hydrogel with antimicrobial and biocompatible properties for infected skin regeneration

A. Sun, X. He, et al.

Discover an innovative injectable hydrogel designed to combat infected wounds! This groundbreaking research by Ao Sun, Xinye He, Lang Li, Tao Li, Qinya Liu, Xinli Zhou, Xiao Ji, Wei Li, and Zhiyong Qian showcases a biocompatible solution with impressive antimicrobial properties, capable of promoting healing in Staphylococcus aureus-infected models.

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Abstract

This paper introduces a novel injectable, photopolymerized hydrogel for treating infected wounds. The hydrogel, composed of modified ε-polylysine (ε-PL) and γ-poly(glutamic acid) (γ-PGA), exhibits biocompatibility and broad-spectrum antimicrobial activity. In vivo studies using Staphylococcus aureus-infected rat models demonstrated the hydrogel's ability to inhibit bacterial infection and promote wound healing, suggesting its potential for clinical applications in antimicrobial and wound healing therapy.

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An injectable photopolymerized hydrogel with antimicrobial and biocompatible properties for infected skin regeneration

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Authors

Ao Sun, Xinye He, Lang Li, Tao Li, Qinya Liu, Xinli Zhou, Xiao Ji, Wei Li, Zhiyong Qian

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