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An engineered ACE2 decoy neutralizes SARS-CoV-2 Omicron BA.5 in vitro and in vivo

Medicine and Health

An engineered ACE2 decoy neutralizes SARS-CoV-2 Omicron BA.5 in vitro and in vivo

H. B., L. G. W., et al.

SARS-CoV-2 continues to evolve, challenging antibody responses. Researchers, including Havranek, Lee, Procko, and others, have developed FLIF, a soluble ACE2 decoy that showcases remarkable neutralization capabilities against the Delta and Omicron variants, including BA.5. This innovative approach has the potential to serve as a therapeutic solution for coronaviruses.

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