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An engineered ACE2 decoy neutralizes SARS-CoV-2 Omicron BA.5 in vitro and in vivo
Medicine and HealthCommunications Biology

An engineered ACE2 decoy neutralizes SARS-CoV-2 Omicron BA.5 in vitro and in vivo

H. B., L. G. W., et al.

SARS-CoV-2 continues to evolve, challenging antibody responses. Researchers, including Havranek, Lee, Procko, and others, have developed FLIF, a soluble ACE2 decoy that showcases remarkable neutralization capabilities against the Delta and Omicron variants, including BA.5. This innovative approach has the potential to serve as a therapeutic solution for coronaviruses.... show more
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Abstract
Publisher
Communications Biology
Published On
May 12, 2023
Authors
Havranek, B., Lee, G. W., Procko, E., Higuchi, Y., Harada, A., Ikemura, N., Sasaki, T., Ohmagari, N., Islam, S. M.
Tags
SARS-CoV-2soluble ACE2FLIFDelta variantOmicron varianttherapeuticneutralization
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