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A single-cell transcriptomic atlas of exercise-induced anti-inflammatory and geroprotective effects across the body

Medicine and Health

A single-cell transcriptomic atlas of exercise-induced anti-inflammatory and geroprotective effects across the body

S. Sun, S. Ma, et al.

This groundbreaking study reveals the powerful effects of long-term aerobic exercise on both physical function and gene expression in young and aged male C57BL/6J mice. The research, conducted by esteemed authors including Shuhui Sun and Shuai Ma, highlights the broad health benefits of exercise, uncovering BMAL1 as a key player in reversing aging-related gene changes and enhancing resilience against infections.

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~3 min • Beginner • English
Abstract
Publisher
The Innovation
Published On
Jan 30, 2023
Authors
Shuhui Sun, Shuai Ma, Yusheng Cai, Si Wang, Jie Ren, Yuanhan Yang, Jiale Ping, Xuebao Wang, Yiyuan Zhang, Haoteng Yan, Wei Li, Concepcion Rodriguez Esteban, Yan Yu, Feifei Liu, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, Guang-Hui Liu
Tags
aerobic exercise
gene expression
aging
C57BL/6J mice
BMAL1
physical performance
inflammation

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