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A fluorescent multi-domain protein reveals the unfolding mechanism of Hsp70
BiologyNature Chemical Biology

A fluorescent multi-domain protein reveals the unfolding mechanism of Hsp70

S. Tiwari, B. Fauvet, et al.

Explore the intriguing mechanism by which Hsp70 chaperones prevent protein aggregation, featuring the novel reporter chaperone substrate MLucV. This research conducted by Satyam Tiwari, Bruno Fauvet, Salvatore Assenza, Paolo De Los Rios, and Pierre Goloubinoff reveals how ATP-fueled actions lead to native MLucV accumulation, even under extreme denaturing conditions!... show more
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