Medicine and Health

Three Outbreaks of COVID-19 in a Single Nursing Home over Two Years of the SARS-CoV-2 Pandemic

V. Čokić, Z. Popovska, et al.

This study investigates the devastation of three COVID-19 outbreaks in a Serbian nursing home, despite the majority of residents and staff being vaccinated with BBIBP-CorV. The findings reveal staggering case fatality rates and highlight how older individuals demonstrated robust immune responses, mitigating mortality in subsequent outbreaks. Conducted by Vladan Čokić, Zorana Popovska, Olivera Lijeskić, Ljiljana Šabić, and Olgica Djurković-Djaković, this research underscores the implications of SARS-CoV-2 variants and vaccine efficacy.

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Abstract

This retrospective study analyzed three COVID-19 outbreaks in a Serbian nursing home during waves of pre-Alpha, Delta, and Omicron variants. Despite vaccination (mostly BBIBP-CorV) of most residents and staff, outbreaks occurred, with case fatality rates of 31.2%, 9.1%, and 0%, respectively. Older individuals showed a good immune response, preventing significant mortality and morbidity in later outbreaks. The study highlights the impact of SARS-CoV-2 variants and vaccine effectiveness, particularly with BBIBP-CorV.

Publisher

Not specified in provided text

Published On

Jan 01, 2023

Authors

Vladan Čokić, Zorana Popovska, Olivera Lijeskić, Ljiljana Šabić, Olgica Djurković-Djaković

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