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Therapeutic efficacy of a MMAE-based anti-DR5 drug conjugate Oba01 in preclinical models of pancreatic cancer

Medicine and Health

Therapeutic efficacy of a MMAE-based anti-DR5 drug conjugate Oba01 in preclinical models of pancreatic cancer

C. Zheng, D. Zhou, et al.

Exciting new research by Chao Zheng and colleagues reveals the impressive antitumor activity of Oba01, an antibody-drug conjugate targeting DR5 in pancreatic cancer. This study shows how Oba01 induces apoptosis and synergizes with gemcitabine, paving the way for innovative therapies for this aggressive disease.

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