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The single-cell transcriptomic atlas iPain identifies senescence of nociceptors as a therapeutical target for chronic pain treatment

Medicine and Health

The single-cell transcriptomic atlas iPain identifies senescence of nociceptors as a therapeutical target for chronic pain treatment

P. Techameena, X. Feng, et al.

Chronic pain affects nearly 20% of adults worldwide and remains inadequately treated. This groundbreaking research by Prach Techameena, Xiaona Feng, Kaiwen Zhang, and Saida Hadjab unveils the role of nociceptor senescence in chronic pain progression. With promising senolytic treatments shown to alleviate pain in mice, the study highlights a potential breakthrough in pain management.

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