This study investigated the impact of acute lifestyle changes during the COVID-19 lockdown on Non-alcoholic fatty liver disease (NAFLD) progression in 187 Italian patients over four years. Lockdown led to increased fat and carbohydrate intake, reduced physical activity, and worsened metabolic parameters. Body composition showed increased fat mass and decreased lean mass. Hepatocellular carcinoma (HCC) incidence significantly increased during lockdown, with a stronger association between HCC and body composition changes than other metabolic factors.
Publisher
Nutrition and Diabetes
Published On
May 27, 2024
Authors
Marcello Dallio, Moris Sangineto, Mario Romeo, Marina Cipullo, Annachiara Coppola, Simone Mammone, Giuseppe Di Gioia, Mario Masarone, Marcello Persico, Gaetano Serviddio, Alessandro Federico
Tags
COVID-19
Non-alcoholic fatty liver disease
hepatocellular carcinoma
lifestyle changes
body composition
metabolic parameters
physical activity
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