This study investigated the association between sucrose intake (self-reported and urinary biomarker) and incident diabetes, considering obesity's mediating role. Using data from a sub-cohort (n=2996) of the EPIC-Norfolk study, inverse associations were found between self-reported sucrose intake and diabetes incidence. However, urinary sucrose showed a positive association with incident diabetes. Mediation analysis revealed that BMI and waist circumference mediated 16% and 22% of this association, respectively. Further research using objective biomarkers is needed.
Publisher
Nutrition & Diabetes
Published On
Sep 02, 2023
Authors
Alexander Lang, Oliver Kuss, Tim Filla, Gunter Kuhnle, Sabrina Schlesinger
Tags
sucrose intake
diabetes incidence
urinary biomarker
obesity
BMI
waist circumference
epidemiology
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