This study investigated the association between body composition and dynamic responses of the pituitary-testis axis in men. A higher BMI was associated with lower basal serum LH and testosterone, and free testosterone. However, the GnRH-stimulated LH increase and HCG-stimulated testosterone increase were less dependent on BMI. Dynamic sex hormone responses following pituitary-testis axis stimulation could potentially assist clinical decision-making in patients with obesity suspected of testosterone deficiency.
Publisher
International Journal of Obesity
Published On
Apr 12, 2024
Authors
Julie Abildgaard, Anne Kirstine Bang, Loa Nordkap, Lærke Priskorn, Niels Jørgensen
Tags
body composition
BMI
pituitary-testis axis
LH
testosterone
obesity
hormonal response
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