Medicine and Health
The evolution of lung cancer and impact of subclonal selection in TRACERx
A. M. Frankell, M. Degasperi, et al.
This groundbreaking study by A M Frankell and colleagues delves into the complexities of lung adenocarcinoma, revealing significant insights into clonal expansion, subclonal selection, and their impact on disease-free survival and relapse. The research uncovers various evolutionary dependencies among cancer genes, highlighting the role of whole genome doubling and copy number instability in NSCLC progression.
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