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Abstract
This study systematically analyzed over 2 million SARS-CoV-2 samples from the European COVID-19 Data Portal to detect co-infections and intra-host recombination. Co-infection was found in 0.35% of samples. Two methods were used to detect recombination, highlighting challenges like PCR artifacts. Three recombination hotspots were identified in Delta and Omicron BA.1 recombinants.
Publisher
Nature Communications
Published On
Jan 15, 2024
Authors
Orsolya Anna Pipek, Anna Medgyes-Horváth, József Stöger, Krisztián Papp, Dávid Visontai, Marion Koopmans, David Nieuwenhuijse, Bas B. Oude Munnik, VEO Technical Working Group, István Csabai
Tags
SARS-CoV-2
co-infections
intra-host recombination
PCR artifacts
recombination hotspots
Delta variant
Omicron BA.1

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