Developing superporous hemostatic sponges with simultaneously enhanced permeability and mechanical properties remains challenging but highly desirable to achieve rapid hemostasis for non-compressible hemorrhage. This paper proposes a temperature-assisted secondary network compaction strategy to fabricate a superporous chitosan sponge with improved properties. The sponge demonstrates rapid shape recovery, enhanced blood absorption, fatigue resistance, and superior hemostatic efficiency compared to commercial alternatives in pig models. The strategy offers a simple and effective method for fabricating hemostatic sponges for various clinical applications.
