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Hollow silica reinforced magnesium nanocomposites with enhanced mechanical and biological properties with computational modeling analysis for mandibular reconstruction

Engineering and Technology

Hollow silica reinforced magnesium nanocomposites with enhanced mechanical and biological properties with computational modeling analysis for mandibular reconstruction

S. Prasadh, V. Manakari, et al.

Explore the groundbreaking research by Somasundaram Prasadh and colleagues on Mg-SiO₂ nanocomposites, which promise remarkable enhancements in biodegradable implants. Their findings reveal how varying silica nanoparticle concentrations can boost strength, corrosion resistance, and biocompatibility, paving the way for innovative solutions in mandibular reconstruction.

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Playback language: English
Abstract
This study investigates Mg-SiO₂ nanocomposites as biodegradable implants. The addition of hollow silica nanoparticles (0.5, 1, and 1.5 vol.%) progressively increased yield and compressive strength, with Mg-1.5 vol.% SiO₂ showing superior enhancement. Nanocomposites exhibited lower corrosion rates than pure Mg, and 1 vol.% SiO₂ addition showed the highest osteoblast cell adhesion and proliferation. Mg-0.5 vol.% SiO₂ showed the best corrosion resistance and biocompatibility. Computational modeling compared the nanocomposite's properties to other mandibular reconstruction biomaterials.
Publisher
International Journal of Oral Science
Published On
Nov 17, 2020
Authors
Somasundaram Prasadh, Vyasaraj Manakari, Gururaj Parande, Raymond Chung Wen Wong, Manoj Gupta
Tags
Mg-SiO₂ nanocomposites
biodegradable implants
hollow silica nanoparticles
osteoblast cell adhesion
corrosion resistance
biocompatibility
mandibular reconstruction

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