Medicine and Health

Response of blood glucose and GLP-1 to different food temperature in normal subject and patients with type 2 diabetes

Y. Hu, P. Zhang, et al.

Discover how food temperature impacts glucose-regulating hormones in different individuals! This research, conducted by Yun Hu, Peng Zhang, Bo Ding, Xin Cao, Yi Zhong, Kok-Onn Lee, and Jian-Hua Ma, unveils surprising effects that could change how we understand glucose absorption and hormonal responses to temperature variations in diets.

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Playback language: English

Index

Abstract

This study investigated the effects of food temperature on glucose-regulating hormones in normal subjects and patients with type 2 diabetes. Both groups underwent oral glucose tolerance tests (OGTTs) with hot (50°C) and cold (8°C) glucose solutions on separate days. Blood glucose, insulin, GIP, GLP-1, and cortisol were measured. Hot OGTTs resulted in significantly higher blood glucose in both groups. However, higher insulin and GLP-1 levels after hot OGTTs were only observed in normal subjects. Continuous glucose monitoring (CGM) revealed higher 24-hour mean glucose in both groups with hot meals, and higher standard deviation of mean blood glucose in normal subjects only. These findings suggest that food temperature significantly influences glucose absorption and GLP-1 response, an effect lost in type 2 diabetes.

Publisher

Nutrition and Diabetes

Published On

May 27, 2022

Authors

Yun Hu, Peng Zhang, Bo Ding, Xin Cao, Yi Zhong, Kok-Onn Lee, Jian-Hua Ma

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