Chemistry

Osmotic pressure enables high yield assembly of giant vesicles in solutions of physiological ionic strengths

A. Cooper, V. Girish, et al.

This groundbreaking research by Alexis Cooper, Vaishnavi Girish, and Anand Bala Subramaniam reveals how osmotic pressure can dramatically enhance the assembly of giant unilamellar vesicles in physiologically relevant conditions. With a focus on the interplay of dissolved polymers and ionic composition, their findings promise to reshape our understanding of vesicle formation and sedimentation behavior.

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Abstract

This paper investigates the high-yield assembly of giant unilamellar vesicles (GUVs) in solutions with physiological ionic strengths. The researchers demonstrate that osmotic pressure plays a crucial role in this process, significantly improving the yield compared to previous methods. They explore the effects of dissolved polymers and ionic composition on vesicle formation and sedimentation behavior.

Publisher

Supporting Information

Published On

Jan 01, 2023

Authors

Alexis Cooper, Vaishnavi Girish, Anand Bala Subramaniam

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