Medicine and HealthNature Communications
Orexin neurons inhibit sleep to promote arousal
R. D. Luca, S. Nardone, et al.
Explore groundbreaking research conducted by Roberto De Luca and colleagues, revealing how orexin neurons play a crucial role in maintaining wakefulness by inhibiting sleep-promoting neurons in the VLPO. This innovative study combines optogenetics and single-cell transcriptomics to uncover the neural circuitry involved in arousal maintenance and behavioral state stabilization.
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